Though published research of whole cannabis is limited, the following information reflects some of the current knowledge.
Cannabis produces ‘cannabinoids’ in tiny resin glands (glandular trichromes) on the outside of the plant.
Over 100 cannabinoids have been identified and plants produce variations in cannabinoid ratios.
The most active cannabinoids stimulate natural human functions to produce therapeutic effects. Synthetic cannabinoids have not proven as effective as whole cannabis extracts.
It is thought the main active cannabinoid is tetrahydrocannabinol-Delta 9, known as THC, there are 10 THC’s.
THC’s have been associated with effects including analgesics, appetite stimulation, anti-epileptic, anti-anemic, anti-inflammatory, bronchio dilation, antidepressant, muscle relaxant.
CBD, Cannabidiol has been associated with analgesic and sedative effects, while modulating psychoactive functions of THC.
CBC, Cannabichromene is thought to promote the analgesic effects of THC and may have sedative properties.
CBG, Cannabigerol may have sedative effects, antimicrobial properties as well as lowering intra-ocular pressure. It is a biogenic precursor of other cannabinoids.
CBN, Cannabinol is a mildly psychoactive degradation of THC. It’s primary effects seem to lower intra-ocular pressure and anti-epileptic.
In addition to cannabinoids, the cannabis plant produces hundreds of other compounds – terpenes and other volatiles, flavinoids, amino acids, fatty acids, proteins, sugars, carbohydrates, simple esters, steroids, nitrogen compounds, vitamins, elements and more.
Terpenes produced within the glandular trichromes are the essential oils which give cannabis its smell. Research shows that certain terpenes may have anti-ulcer and anti-mutagenic potential.
We believe that various components of the cannabis plant beneficially modulate the effects of THC, CBD, CBN and other cannabinoids while exerting helpful effects on their own.